Leanne Groban Selected Research

human angiotensin-(1-12)

1/2022

Immunoneutralization of human angiotensin-(1-12) with a monoclonal antibody in a humanized model of hypertension.

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Leanne Groban Research Topics

Disease

13	Hypertension (High Blood Pressure) 04/2022 - 05/2008
11	Fibrosis (Cirrhosis) 01/2017 - 10/2007
9	Heart Failure 12/2021 - 01/2017
9	Heart Diseases (Heart Disease) 04/2021 - 09/2006
6	Cardiovascular Diseases (Cardiovascular Disease) 04/2022 - 05/2011
6	Ventricular Remodeling 12/2021 - 01/2006
5	Left Ventricular Dysfunction 12/2021 - 07/2015
5	Hypertrophy 04/2012 - 10/2007
4	Inflammation (Inflammations) 01/2019 - 02/2008
4	Myocardial Ischemia (Ischemic Heart Diseases) 01/2017 - 04/2004
3	Stroke (Strokes) 04/2021 - 01/2020
3	COVID-19 01/2021 - 01/2020
3	Atrial Fibrillation 08/2020 - 08/2015
2	Cardiomegaly (Heart Hypertrophy) 01/2022 - 06/2010
2	Obesity 12/2021 - 10/2020
2	Chronic Obstructive Pulmonary Disease (COPD) 04/2021 - 01/2015
2	Frailty 11/2017 - 04/2016
2	Pain (Aches) 04/2016 - 11/2010
2	Insulin Resistance 05/2015 - 05/2008
2	Proteinuria 02/2013 - 10/2007
1	Knee Osteoarthritis 04/2021
1	Essential Hypertension 01/2021
1	Multiple Endocrine Neoplasia Type 2a (MEN 2) 01/2021
1	Infections 10/2020
1	Body Weight (Weight, Body) 01/2019
1	Cognitive Dysfunction 11/2017
1	Delirium 11/2017
1	Ischemic Stroke 10/2017
1	Atherosclerosis 10/2017
1	Ischemia 01/2017
1	Myocardial Infarction 01/2017
1	Pathologic Processes 07/2016
1	Vascular Diseases (Vascular Disease) 01/2016
1	Vascular Remodeling 01/2016
1	Heart Valve Diseases (Valvular Heart Disease) 08/2015
1	Obstructive Sleep Apnea 01/2015
1	Malnutrition (Nutritional Deficiencies) 01/2015
1	Dementia (Dementias) 01/2015

Drug/Important Bio-Agent (IBA)

10	Estrogens (Estrogen)FDA Link 12/2021 - 06/2011
9	Angiotensin IIIBA 04/2022 - 08/2009
7	Estrogen ReceptorsIBA 11/2021 - 07/2015
7	Chymases (Chymase)IBA 08/2020 - 05/2014
6	ReninIBA 04/2022 - 08/2009
6	GTP-Binding Proteins (G-Protein)IBA 11/2021 - 03/2014
5	AngiotensinsIBA 04/2022 - 02/2017
5	Hormones (Hormone)IBA 12/2021 - 06/2011
5	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 10/2020 - 08/2009
5	SaltsIBA 01/2017 - 10/2007
4	AngiotensinogenIBA 01/2021 - 05/2014
4	CollagenIBA 01/2017 - 06/2010
3	Pharmaceutical PreparationsIBA 04/2021 - 09/2006
3	Angiotensin-Converting Enzyme 2IBA 01/2021 - 06/2010
3	Proteins (Proteins, Gene)FDA Link 10/2020 - 12/2009
3	Messenger RNA (mRNA)IBA 08/2020 - 04/2012
3	CalciumIBA 01/2019 - 01/2002
2	AldosteroneIBA 04/2022 - 01/2008
2	Peptides (Polypeptides)IBA 04/2022 - 06/2010
2	Antihypertensive Agents (Antihypertensives)IBA 01/2021 - 02/2013
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2019 - 03/2014
2	Angiotensin Receptor AntagonistsIBA 02/2017 - 08/2009
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2017 - 08/2013
2	salicylhydroxamic acid (SHAM)IBA 01/2017 - 01/2017
2	C-Reactive ProteinIBA 04/2016 - 10/2007
2	LipidsIBA 05/2015 - 11/2006
2	angiotensin I (1-7)IBA 06/2010 - 02/2010
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022
1	Monoclonal AntibodiesIBA 01/2022
1	human angiotensin-(1-12)IBA 01/2022
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 04/2021
1	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA 04/2021
1	Serine Proteases (Serine Protease)IBA 01/2021
1	pro-brain natriuretic peptide (1-76)IBA 01/2021
1	Metalloproteases (Metalloproteinases)IBA 01/2021
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2020
1	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 01/2019
1	Interleukin-18 (Interleukin 18)IBA 01/2019
1	InflammasomesIBA 01/2019
1	Antidepressive Agents (Antidepressants)IBA 10/2017
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 10/2017
1	Sertraline (Zoloft)FDA LinkGeneric 10/2017
1	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 01/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017
1	LASSBio 294IBA 01/2017
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 01/2017
1	Cromolyn Sodium (Cromoglicic Acid)FDA LinkGeneric 07/2016
1	Angiotensin IIBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 05/2015
1	Insulin (Novolin)FDA Link 05/2015
1	CholesterolIBA 05/2015
1	Oxygen (Dioxygen)IBA 01/2015

Therapy/Procedure

9	Therapeutics 04/2022 - 08/2009
2	Ovariectomy (Oophorectomy) 01/2017 - 08/2013
2	Anesthesia 11/2006 - 09/2006
1	Knee Replacement Arthroplasty (Total Knee Replacement) 04/2021
1	Preoperative Exercise 04/2021
1	Self Medication 11/2017
1	Institutionalization (Institutionalized Persons) 11/2017
1	Perioperative Period 11/2017
1	Oral Administration 01/2017
1	Airway Management 01/2015